Discover the Modular Optical Imaging System (OiS200)

The Modular Optical Imaging System (OiS200) from LabeoTech is a cutting-edge platform designed to meet the diverse needs of researchers in the field of brain imaging. This versatile system supports a range of optical imaging techniques, including Widefield Intrinsic signal Optical Imaging, Fluorescence Imaging, and Speckle Imaging, making it an essential tool for modern neuroscience.

What is Optical Imaging?

Optical imaging is a technique that uses light interactions to measure brain activity. Compared to other imaging methods, optical imaging provides high-resolution images both temporally and spatially with minimal invasiveness, making it ideal for an assortment of applications. By leveraging advanced optical imaging techniques, researchers can gain deeper insights into biological processes.

Advantages of Optical Imaging

High-Resolution Images

Optical imaging provides higher resolution images at a faster frame rate when compared to fMRI.

Non-Invasive Techniques

Optical imaging captures detailed images without invasive procedures, reducing discomfort. Also, this technique can be used for both acute and chronic experiments.

Cost-Effectiveness and Speed

Optical imaging is usually faster and cheaper than other methods, as fMRI or ultrasounds. This allows for quicker data collection and lowers overall costs.

Advanced Optical Imaging Techniques

The OiS200 excels in optical imaging methods highly effective for observing brain activity in vivo. Whether working with awake or anesthetized mice, researchers can utilize intrinsic optical imaging and fluorescence imaging to capture detailed views of neural dynamics. The system’s speckle imaging capability further enhances its utility by allowing precise quantification of cerebral blood flow across surface vessels.

Optogenetic Stimulation for Enhanced Imaging

To push the boundaries of optical imaging, the OiS200 can be completed  by an optional integrated optogenetic stimulation module. Researchers can choose between two configurations: a single point that can be moved across the brain or a full 8.5 mm x 8.5 mm spatially modulated pattern. Multiple wavelengths are available to stimulate different opsins, including ChR2 and Chrimson, ensuring compatibility with a wide range of experimental setups.

User-Friendly and Configurable Imaging Platform

Designed with flexibility, the OiS200 is portable and easy to set up, making it ideal for various research environments. The optical imaging system offers multiple camera options and illumination solutions, all controlled via a user-friendly software interface. This ensures that researchers can tailor the system to their specific needs without compromising ease of use.

Customizable Setup and High-Quality Construction

The OiS200 allows users to adjust imaging angles up to ±30º for better optical imaging. You can change the height of the system. You can also set up the lights in different ways for your experiments. Strong steel makes the imaging plate. This allows for magnetic accessories to be used for a secure and flexible setup.

Explore New Frontiers with Our Microendoscope

LabeoTech developed a new microendoscope add-on working with the OiS200 platform.

This device can observe deep brain activity in awake, freely moving animals. This new tool improves optical imaging. It lets researchers study brain function in ways that were not possible before.

All publications with our imaging system can be viewed here.

Vertical Positioning

Inclination

Multiple cameras

Behavioral Monitoring Camera

Unlock the full potential of your research with our add-on behavioral monitoring camera designed specifically for monitoring mouse behavior.

Key Features:

  • High-Speed Recording: Capture rapid movements and subtle behaviors at up to 900 fps (256 X 128).
  • Infrared Illumination: Monitor your subjects in dark conditions without disturbing their natural behavior and the imaging system.
  • Synchronization with Imaging System: Seamlessly integrated to the acquisition software for precise synchronization (0.1 ms) with the main imaging camera, the analog inputs and the output stimulations.
  • Adjustable Zoom: Focus on specific areas or behaviors with ease, such as the pupil or the paws, thanks to the adjustable zoom feature.

Whether you’re conducting behavioral studies, neurological research, or any other scientific investigation, our camera provides the reliability and performance you need to achieve your research goals.

Here are the potential applications for using our modular optical imaging system:

  • Cerebral blood flow, neurovascular coupling & functional connectivity studies
  • Neurological disorders
  • Pharmacology
  • Optogenetics
  • Voltage sensitive dies (VSD)
  • Electrophysiology (compatible with Open Ephys)
  • Epilepsy
  • Alzheimer’s disease
  • Aging
  • Hypertension
  • Ischemia
  • Strokes
  • Awake head-fixed mice

Accessories for the OiS200 can be purchased from our online store

Accessories for the OiS200 can be purchased from our online store

Specifications
Dimensions
1.5′ (width) X 2′ (depth) X 2′ (height)
Frame Rate
50 fps at 1024 X 1024, up to 1000 fps
Exposure Time
>0.1 ms
Output Stimulation
Digital (8 bits) and Analog (2 channels)
Inputs
8 inputs, 10 kSamples/second

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